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Organic compounds with acidic properties, organic acids are generally weak acids incapable of complete dissociation in water. Available in a range of chemical compositions and acid strengths, they can be used for various industrial and everyday applications.
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Quilseconazole Formic acid is a selective inhibitor of fungal Cyp51 with potent activities against Cryptococcus neoformans and Cryptococcus gattii.
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Zelavespib formic (PU-H71 formic) is a potent Hsp90 inhibitor with an IC50 value of 51 nM for Hsp90 in MDA-MB-468 cells. It is intended for research use only.
Potent Hsp90 inhibitor
Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO
Available in various solid forms (5 mg, 10 mg, 25 mg, 50 mg, 100 mg)
Also available in solution form (10 mM * 1 mL in DMSO)
Cited in 12 publications
Related to various compound screening libraries and small molecules
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Ro 31-8220 formic is the formic acid salt of bisindolylmaleimide IX, a potent protein kinase C (PKC) inhibitor provided for laboratory research. The compound is supplied as a small, high-purity solid with manufacturer storage and handling guidance available on the product datasheet.
Potent PKC inhibitor with low-nanomolar activity.
Formic acid salt for improved handling and solubility options.
High purity (≈96.0%).
Orange to red solid appearance.
Supplied as a 5 mg vial for research use.
Recommended storage: sealed, away from moisture, at -20 °C; in solvent, store at -80 °C (up to 6 months) or -20 °C (up to 1 month).
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CBI1 formic is a covalent BAX inhibitor. It selectively derivatizes BAX at C126 and inhibits BAX activation by triggering ligands or point mutagenesis. CBI1 formic blocks t-2-hex lipidation and oligomerization of BAX and inhibits BAX activation induced by BH3 ligands, F116A mutagenesis or t-2-hex.
Covalent BAX inhibitor
Selectively derivatizes BAX at C126
Inhibits BAX activation by triggering ligands or point mutagenesis
Blocks t-2-hex lipidation and oligomerization of BAX
Inhibits BAX activation induced by BH3 ligands, F116A mutagenesis or t-2-hex
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PKCiota-IN-2 formic is a research-grade small-molecule inhibitor targeting atypical protein kinase C iota (PKCι). It exhibits low-nanomolar potency and a defined selectivity profile, and is supplied as a powder for laboratory use with recommended sealed, refrigerated storage.
Low-nanomolar potency against PKCι (IC50 2.8 nM).
Inhibits PKCα and PKCε with higher IC50s (71 nM and 350 nM).
High chemical purity (99.04%).
Molecular weight 402.36 g·mol⁻¹.
Provided as a powder with refrigerated storage recommended.
Available in small research pack sizes (including 5 mg).
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Formic Acid is the simplest carboxylic acid containing only one carbon. It is a colorless liquid with a pungent aroma. It is about 10 times stronger than Acetic Acid. The high acidity level and reducing nature of this compound makes it different from other carboxylic acids. LC/MS is a versatile technique that combines the physical separation property of Liquid Chromatography with the mass analysis property of Mass Spectroscopy. LC-MS Grade Formic Acid is high-purity solvent for preparing elution solvents for HPLC separations of protein and peptides. LC/MS Grade Formic Acid is well suited as a chromatography additive for use in LCMS and HPLC applications.
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LCC-12 formic is a dimer of metformin that targets mitochondrial copper(II), leading to a decrease in the NAD(H) pool and modulation of inflammatory responses. It reduces inflammation in mouse models of bacterial and viral infections and serves as a tool for investigating metabolic diseases through its effects on cell plasticity and epigenetic programming.
Targets mitochondrial copper(II)
Leads to a decrease in the NAD(H) pool
Modulates inflammatory responses
Reduces inflammation in mouse models of bacterial and viral infections
Serves as a tool for investigating metabolic diseases
Affects cell plasticity and epigenetic programming
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